Surface plasmon resonance (SPR) is a sensitive, label-free technique that detects mass changes due to biomolecular interactions on a surface. This versatile method has been used to evaluate the specificity and binding kinetics of molecules, ranging from short oligonucleotides to whole cells. In this webinar, we will discuss the use of SPR to investigate interactions between aptamers and their targets, as well as the triggered formation of DNA polymers and polyvalent aptamers. In addition, the use of oligonucleotides for the release of protein drugs will be discussed.

Learning Objectives:

• Learn the principles of Surface Plasmon Resonance (SPR)
• Learn how to do SPR data analysis
• Learn what aptamers are

Speaker:

Erin Gaddes
2016 PhD Graduate
Department of Bioengineering
Penn State University

Erin received her Ph.D. and Master’s degrees in Bioengineering from Pennsylvania State University, and her Bachelors in Chemical and Biomolecular Engineering from the University of Notre Dame. Prior to becoming a registered patent agent, she pursued industrial post-doctoral work in the field of immunology. She has demonstrated success in pursuing a U.S. patent and co-authoring nine peer-reviewed research articles.